Cholinergic Drugs
Acetylcholine mimics and cholinesterase inhibitors
Direct-acting: choline esters
Acetylcholine
Classification: Direct-acting: choline esters
Methacholine
Classification: Direct-acting: choline esters
Carbachol
Classification: Direct-acting: choline esters
Bethanechol
Classification: Direct-acting: choline esters
Direct-acting: alkaloids
Pilocarpine
Classification: Direct-acting: alkaloids
Muscarine
Classification: Direct-acting: alkaloids
Indirect-acting: reversible AChE inhibitors
Edrophonium
Classification: Indirect-acting: reversible AChE inhibitors
Neostigmine
Classification: Indirect-acting: reversible AChE inhibitors
Physostigmine
Classification: Indirect-acting: reversible AChE inhibitors
Pyridostigmine
Classification: Indirect-acting: reversible AChE inhibitors
Donepezil
Classification: Indirect-acting: reversible AChE inhibitors
Rivastigmine
Classification: Indirect-acting: reversible AChE inhibitors
Galantamine
Classification: Indirect-acting: reversible AChE inhibitors
Indirect-acting: irreversible AChE inhibitors
Echothiophate
Classification: Indirect-acting: irreversible AChE inhibitors
Organophosphates (e.g., malathion, soman)
Classification: Indirect-acting: irreversible AChE inhibitors
Related antidote (not a cholinergic agonist)
Pralidoxime
Classification: Related antidote (not a cholinergic agonist)
AChE reactivator in organophosphate poisoning
SOURCE / SCOPE NOTE
- Lectures 11–12. Some listed agents appear in an overview marked “Don’t memorize”; include them as reference, not automatically as required exam material.
